abstract：:Environmental issues tend to greater political attention than do environmental health aspects. Therefore, when conflicts of interest occur with other environmental concerns, negative consequences for public health may result. For example, a strategy to substantially reduce indoor ventilation in many dwellings in Sca...

journal_title：BMJ (Clinical research ed.)

authors： Pershagen G

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVES:To quantify the relative contribution of premorbid and episode specific factors in determining the long term persistence of disabling symptoms of low back pain. DESIGN:Prospective cohort study. SETTING:Two general practices in the south Manchester area. PARTICIPANTS:180 patients, who previously participat...

journal_title：BMJ (Clinical research ed.)

authors： Thomas E,Silman AJ,Croft PR,Papageorgiou AC,Jayson MI,Macfarlane GJ

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVE:To examine the effect of the method of data display on physician investigators' decisions to stop hypothetical clinical trials for an unplanned statistical analysis. DESIGN:Prospective, mixed model design with variables between subjects and within subjects (repeated measures). SETTING:Comprehensive cancer c...

journal_title：BMJ (Clinical research ed.)

authors： Elting LS,Martin CG,Cantor SB,Rubenstein EB

更新日期：1999-06-05 00:00:00

abstract：OBJECTIVES:To investigate whether sending patients a copy of their referral letter can reduce non-attendance at outpatient departments. DESIGN:Blinded randomised controlled trial. SETTING:13 general practices in Exeter, Devon. SUBJECTS:2078 new consultant referrals from 26 doctors. MAIN OUTCOME MEASURES:Non-attenda...

journal_title：BMJ (Clinical research ed.)

authors： Hamilton W,Round A,Sharp D

更新日期：1999-05-22 00:00:00

abstract：OBJECTIVE:To describe the clinical circumstances in which psychiatric patients commit suicide. DESIGN:National clinical survey. SETTING:England and Wales. SUBJECTS:A two year sample of people who had committed suicide, in particular those who had been in contact with mental health services in the 12 months before de...

journal_title：BMJ (Clinical research ed.)

authors： Appleby L,Shaw J,Amos T,McDonnell R,Harris C,McCann K,Kiernan K,Davies S,Bickley H,Parsons R

更新日期：1999-05-08 00:00:00

abstract：OBJECTIVES:To investigate the effect of Chlamydia pneumoniae infection on future development of ischaemic heart disease and mortality. DESIGN:Prospective longitudinal study. SETTING:Caerphilly, South Wales. SUBJECTS:Plasma specimens were collected during 1979-83 from 1773 men aged 45-59 years. These were tested for ...

journal_title：BMJ (Clinical research ed.)

authors： Strachan DP,Carrington D,Mendall MA,Ballam L,Morris J,Butland BK,Sweetnam PM,Elwood PC

更新日期：1999-04-17 00:00:00

abstract：OBJECTIVE:To assess the direct and indirect effects of being a twin, maternal smoking, birth weight, and mother's height on blood pressure at ages 9 and 18 years. DESIGN:Longitudinal study. SUBJECTS:Cohort born in 1972-3. SETTING:Dunedin, New Zealand. MAIN OUTCOME MEASURE:Blood pressure at ages 9 and 18 years. RES...

journal_title：BMJ (Clinical research ed.)

authors： Williams S,Poulton R

更新日期：1999-04-03 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of day hospital attendance in prolonging independent living for elderly people. DESIGN:Systematic review of 12 controlled clinical trials (available by January 1997) comparing day hospital care with comprehensive care (five trials), domiciliary care (four trials), or no comprehen...

journal_title：BMJ (Clinical research ed.)

authors： Forster A,Young J,Langhorne P

更新日期：1999-03-27 00:00:00

abstract：:Since the World Health Organization (WHO) set a goal in 1988 of eradicating polio worldwide by 2000, the incidence of the disease has declined by 90% around the world, with national immunization days conducted in more than 120 countries. More than 450 million children were immunized in 1998 alone. Now, with only abo...

journal_title：BMJ (Clinical research ed.)

authors： Mach A

更新日期：1999-03-20 00:00:00

abstract：OBJECTIVE:To evaluate the effect on general practitioners' prescribing of feedback on their levels of prescribing. DESIGN:Randomised controlled trial. SETTING:General practice in rural Australia. PARTICIPANTS:2440 full time recognised general practitioners practising in non-urban areas. INTERVENTION:Two sets of gra...

journal_title：BMJ (Clinical research ed.)

authors： O'Connell DL,Henry D,Tomlins R

更新日期：1999-02-20 00:00:00

abstract：OBJECTIVES:To determine the number and geographical distribution of general practitioners in the NHS who qualified medically in South Asia and to project their numbers as they retire. DESIGN:Retrospective analysis of yearly data and projection of future trends. SETTING:England and Wales. SUBJECTS:General practitione...

journal_title：BMJ (Clinical research ed.)

authors： Taylor DH Jr,Esmail A

更新日期：1999-01-30 00:00:00

abstract：:In Oregon, Planned Parenthood and a group of physicians who perform abortions have filed a civil suit against several anti-abortion groups individuals. The suit seeks $200 million in damages and an injunction to bar the defendants from posting information on the Internet that threatens the lives and well-being of the...

journal_title：BMJ (Clinical research ed.)

authors： Charatan F

更新日期：1999-01-23 00:00:00

abstract：OBJECTIVES:To determine the prevalence of workplace bullying in an NHS community trust; to examine the association between bullying and occupational health outcomes; and to investigate the relation between support at work and bullying. DESIGN:Questionnaire survey. SETTING:NHS community trust in the south east of Engl...

journal_title：BMJ (Clinical research ed.)

authors： Quine L

更新日期：1999-01-23 00:00:00

abstract：:This article presents a study on the sexual lifestyle of long distance lorry drivers in India. Using a questionnaire survey method, a total of 5709 consecutive long distance lorry drivers were interviewed by three trained investigators between March 1994 and August 1994. Results showed that 87% (4949 men) of subject...

journal_title：BMJ (Clinical research ed.)

authors： Rao KS,Pilli RD,Rao AS,Chalam PS

更新日期：1999-01-16 00:00:00

abstract：OBJECTIVES:To determine clinical correlates and outcome of hypoxaemia in children admitted to hospital with an acute lower respiratory tract infection. DESIGN:Prospective cohort study. SETTING:Paediatric wards of the Royal Victoria Hospital and the hospital of the Medical Research Council's hospital in Banjul, the Ga...

journal_title：BMJ (Clinical research ed.)

authors： Usen S,Weber M,Mulholland K,Jaffar S,Oparaugo A,Omosigho C,Adegbola R,Greenwood B

更新日期：1999-01-09 00:00:00

abstract：OBJECTIVE:To determine the prevalence of severe psychological trauma --that is, post-traumatic stress disorder--in children involved in everyday road traffic accidents. DESIGN:12 month prospective study. SETTING:Accident and emergency department, Royal United Hospital, Bath. SUBJECTS:119 children aged 5-18 years inv...

journal_title：BMJ (Clinical research ed.)

authors： Stallard P,Velleman R,Baldwin S

更新日期：1998-12-12 00:00:00

abstract：OBJECTIVE:To investigate the psychosocial factors associated with consultation for low back pain. DESIGN:Two phase cross sectional postal survey. SETTING:Bradford Metropolitan Health District. SUBJECTS:1813 adults responding to the phase 1 questionnaire. 540 of the 782 with an episode of low back pain in the past 12...

journal_title：BMJ (Clinical research ed.)

authors： Waxman R,Tennant A,Helliwell P

更新日期：1998-12-05 00:00:00

abstract：:The International AIDS Vaccine Initiative, based in New York, US, was established in 1996 to develop a safe and affordable AIDS vaccine. It is funded by a number of large foundations and charities, the British government, and the World Bank. The Initiative's first 2 large projects, 2 research programs into a vaccine...

journal_title：BMJ (Clinical research ed.)

authors： Matthews H

更新日期：1998-12-05 00:00:00

abstract：OBJECTIVE:To investigate any long term effects of traumatic birth and obstetric procedures in relation to suicide by violent means in offspring as adults. DESIGN:Prospective case-control study. SETTING:Stockholm, Sweden. SUBJECTS:242 adults who committed suicide by violent means from 1978 to 1995, and who were born ...

journal_title：BMJ (Clinical research ed.)

authors： Jacobson B,Bygdeman M

更新日期：1998-11-14 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of corticosteroid injections with physiotherapy for the treatment of painful stiff shoulder. DESIGN:Randomised trial. SETTING:40 general practices. SUBJECTS:109 patients consulting general practitioners for shoulder pain were enrolled in the trial. INTERVENTIONS:Patients were ...

journal_title：BMJ (Clinical research ed.)

authors： van der Windt DA,Koes BW,Devillé W,Boeke AJ,de Jong BA,Bouter LM

更新日期：1998-11-07 00:00:00

abstract：OBJECTIVE:To provide a comprehensive survey of the content and quality of intervention studies relevant to the treatment of schizophrenia. DESIGN:Data were extracted from 2000 trials on the Cochrane Schizophrenia Group's register. MAIN OUTCOME MEASURES:Type and date of publication, country of origin, language, size o...

journal_title：BMJ (Clinical research ed.)

authors： Thornley B,Adams C

更新日期：1998-10-31 00:00:00

abstract：OBJECTIVE:To compare the implications of four widely used cholesterol screening and treatment guidelines by applying them to a population in the United Kingdom. DESIGN:Guidelines were applied to population based data from a cross sectional study of cardiovascular disease and risk factors. SETTING:Newcastle upon Tyne,...

journal_title：BMJ (Clinical research ed.)

authors： Unwin N,Thomson R,O'Byrne AM,Laker M,Armstrong H

更新日期：1998-10-24 00:00:00

abstract：OBJECTIVE:To evaluate the impact of the revised diagnostic criteria for diabetes mellitus adopted by the American Diabetes Association on prevalence of diabetes and on classification of patients. For epidemiological purposes the American criteria use a fasting plasma glucose concentration >=7.0 mmol/l in contrast with ...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1998-08-08 00:00:00

abstract：OBJECTIVES:To describe utilisation of general practitioners by elderly people resident in communal establishments; to examine variations in general practitioner utilisation and estimate the likely impact of the "downsizing" of long stay provision in NHS hospitals. DESIGN:Secondary analyses of the survey of disability ...

journal_title：BMJ (Clinical research ed.)

authors： Kavanagh S,Knapp M

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To evaluate an experimental heroin maintenance programme. DESIGN:Randomised trial. SETTING:Outpatient clinic in Geneva, Switzerland. SUBJECTS:Heroin addicts recruited from the community who were socially marginalised and in poor health and had failed in at least two previous drug treatments. INTERVENTION:...

journal_title：BMJ (Clinical research ed.)

authors： Perneger TV,Giner F,del Rio M,Mino A

更新日期：1998-07-04 00:00:00

abstract：OBJECTIVE:To compare effectiveness and acceptability of early discharge to a hospital at home scheme with that of routine discharge from acute hospital. DESIGN:Pragmatic randomised controlled trial. SETTING:Acute hospital wards and community in north of Bristol, with a catchment population of about 224 000 people. S...

journal_title：BMJ (Clinical research ed.)

authors： Richards SH,Coast J,Gunnell DJ,Peters TJ,Pounsford J,Darlow MA

更新日期：1998-06-13 00:00:00

abstract：:Lifetime fertility, abortion rates, and the proportion of pregnancies resulting in induced abortion were investigated in 105 district health authorities in England. In 1995, a total of 147,851 abortions occurred among women living in England, compared with 613,257 live births; a ratio of 1:4. This was equivalent to ...

journal_title：BMJ (Clinical research ed.)

authors： Raleigh VS

更新日期：1998-06-06 00:00:00

abstract：OBJECTIVE:To analyse the cost effectiveness of a national programme to screen blood donors for infection with the human T cell leukaemia/lymphoma virus. DESIGN:Three models for calculating the costs and benefits of screening were developed. The first model analysed the cost of continuously testing all donations; the s...

journal_title：BMJ (Clinical research ed.)

authors： Tynell E,Andersson S,Lithander E,Arneborn M,Blomberg J,Hansson HB,Krook A,Nomberg M,Ramstedt K,Shanwell A,Bjorkman A

更新日期：1998-05-09 00:00:00

abstract：OBJECTIVES:To investigate the claim that 90% of episodes of low back pain that present to general practice have resolved within one month. DESIGN:Prospective study of all adults consulting in general practice because of low back pain over 12 months with follow up at 1 week, 3 months, and 12 months after consultation. ...

journal_title：BMJ (Clinical research ed.)

authors： Croft PR,Macfarlane GJ,Papageorgiou AC,Thomas E,Silman AJ

更新日期：1998-05-02 00:00:00

abstract：OBJECTIVES:To provide a contemporary account of the treatment and outcomes of acute coronary attacks in England and Wales and to identify strategies that might improve the outcome. DESIGN:Two year community and hospital based study in three British health districts. SETTING:Health districts of Brighton (population 28...

journal_title：BMJ (Clinical research ed.)

authors： Norris RM

更新日期：1998-04-04 00:00:00

abstract：OBJECTIVE:To determine whether short-term, oral low dose prednisolone (< or = 15 mg daily) is superior to placebo and non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis. DESIGN:Meta-analysis of randomised trials of oral corticosteroids compared with placebo or a non-steroidal anti-inflammatory...

journal_title：BMJ (Clinical research ed.)

authors： Gøtzsche PC,Johansen HK

更新日期：1998-03-14 00:00:00

abstract：OBJECTIVE:To investigate whether users of oral contraceptives and in [corrected] carriers of a hereditary prothrombotic condition (factor V Leiden mutation, protein C, S, or antithrombin deficiency) have an increased risk of cerebral sinus thrombosis. DESIGN:Comparison of a prospective series of cases of cerebral sinu...

journal_title：BMJ (Clinical research ed.)

authors： de Bruijn SF,Stam J,Koopman MM,Vandenbroucke JP

更新日期：1998-02-21 00:00:00

abstract：OBJECTIVE:To examine the relation between energy intake in childhood and adult mortality from cancer. STUDY DESIGN:Cohort study. SETTING:16 rural and urban centres in England and Scotland. SUBJECTS:3834 people who took part in Lord Boyd Orr's Carnegie survey of family diet and health in prewar Britain between 1937 a...

journal_title：BMJ (Clinical research ed.)

authors： Frankel S,Gunnell DJ,Peters TJ,Maynard M,Davey Smith G

更新日期：1998-02-14 00:00:00

abstract：OBJECTIVE:To test the hypothesis of an association between neonatal intramuscular vitamin K and childhood leukaemia and other cancers. DESIGN:Population based case-control study with data abstracted from hospital records. SETTING:Scotland. SUBJECTS:Children aged 0-14 years resident in Scotland from 1991-4 and diagno...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Juszczak E,Findlay E,Smith K

更新日期：1998-01-17 00:00:00

abstract：OBJECTIVE:To evaluate the safety of withholding anticoagulant treatment from patients with clinically suspected deep vein thrombosis but normal findings on compression ultrasonography. DESIGN:Compression ultrasonography was done with a simplified diagnostic procedure limited to the common femoral vein in the groin and...

journal_title：BMJ (Clinical research ed.)

authors： Cogo A,Lensing AW,Koopman MM,Piovella F,Siragusa S,Wells PS,Villalta S,Büller HR,Turpie AG,Prandoni P

更新日期：1998-01-03 00:00:00

abstract：OBJECTIVE:To estimate the risk of having a low birthweight infant associated with changes in social, environmental, and genetic factors. DESIGN:Population based, historical cohort study using the Danish medical birth registry and Statistic Denmark's fertility database. SUBJECTS:All women who had a low birthweight inf...

journal_title：BMJ (Clinical research ed.)

authors： Basso O,Olsen J,Johansen AM,Christensen K

更新日期：1997-12-06 00:00:00

abstract：OBJECTIVES:To assess, as part of wider inspections by HM Inspectorate of Prisons, the extent and quality of health care in prisons in England and Wales. DESIGN:Inspections based on a set of "expectations" derived mainly from existing healthcare quality standards published by the prison service and existing ethical gui...

journal_title：BMJ (Clinical research ed.)

authors： Reed J,Lyne M

更新日期：1997-11-29 00:00:00

abstract：OBJECTIVES:To investigate the effect of milk supplementation on total body bone mineral acquisition in adolescent girls. DESIGN:18 month, open randomised intervention trial. SUBJECTS:82 white girls aged 12.2 (SD 0.3) years, recruited from four secondary schools in Sheffield. INTERVENTION:568 ml (one pint) of whole o...

journal_title：BMJ (Clinical research ed.)

authors： Cadogan J,Eastell R,Jones N,Barker ME

更新日期：1997-11-15 00:00:00

abstract：OBJECTIVE:To investigate the association between birth weight of offspring and mortality among fathers and mothers in the west of Scotland. DESIGN:Prospective observational study. PARTICIPANTS:794 married couples in Renfrew district of the west of Scotland. MAIN OUTCOME MEASURES:Mortality from all causes and from ca...

journal_title：BMJ (Clinical research ed.)

authors： Davey Smith G,Hart C,Ferrell C,Upton M,Hole D,Hawthorne V,Watt G

更新日期：1997-11-08 00:00:00

abstract：OBJECTIVES:To investigate the consequences of longstanding obesity on left ventricular mass and structure and to examine the effects of weight loss on these variables. DESIGN:Cross sectional survey and controlled intervention study. SETTING:City of Gothenburg and surrounding areas. Sweden. SUBJECTS:41 obese patients...

journal_title：BMJ (Clinical research ed.)

authors： Karason K,Wallentin I,Larsson B,Sjöström L

更新日期：1997-10-11 00:00:00